20240805143557_7091
20240805143609_6290
20240805143621_3897
20240805143557_7091
20240805143609_6290
20240805143621_3897

EDDP Rapid Test

The EDDP (Methadone Metabolite) Rapid Test Strip/Panel/Cassette (Urine) is a rapid immunochromatographic assay for the qualitative detection of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), an inactive metabolite of methadone that acts as a narcotic pain reliever and is used as a treatment for opiate addiction. This assay provides only a preliminary analytical test result. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/mass spectrometry (GC/MS) is the preferred confirmatory method. Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are used.

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Description

Technical Parameters

advantage

Easy to use
No equipment required
High sensitivity and specificity
Fast results at 5 minutes

Summary

Methadone is an unusual drug in that its primary urinary metabolites (EDDP and EMDP) are cyclic in structure, making them very difficult to detect using immunoassays targeted to the native compound.1 Exacerbating this problem, there is a subsection of the population classified as "extensive metabolizers" of methadone. In these individuals, a urine specimen may not contain enough parent methadone to yield a positive drug screen even if the individual is in compliance with their methadone maintenance. EDDP represents a better urine marker for methadone maintenance than unmetabolized methadone. The EDDP Rapid Test Panel (Urine) is a rapid urine screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of EDDP in urine. The EDDP Rapid Test Panel (Urine) yields a positive result when EDDP in urine exceeds 300 ng/mL.

Convenient Procedure

product-526-196

Allow the test, urine specimen, and/or controls to reach room temperature (15-30ºC) prior to testing.

1. Bring the pouch to room temperature before opening it. Remove the test panel from the sealed pouch and use it within one hour.

2. Remove the cap.

3. With the arrow pointing toward the urine specimen, immerse the test panel vertically in the urine specimen for at least 10 to 15 seconds. Immerse the strip to at least the level of the wavy lines, but not above the arrow on the test panel.

4. Replace the cap and place the test panel on a non-absorbent flat surface.

5. Start the timer and wait for the colored line(s) to appear.

6. The result should be read at 5 minutes. Results may be stable up to 10 minutes after test initiation.