G6PD Rapid Test

• Easy to use
• No equipment required
• High sensitivity and specificity
• Fast results 

Gluclose-6-phosphate dehydrogenase(G6PD) is a hereditary disease caused by a defect in the G6PD enzyme of red blood cell membranes. This defect leads to a decrease in the production of reduced nicotinamide adenine dinucleotide phosphate(NADPH), which is essential for maintaining the stability of red blood cell membranes and protecting against oxidative damage. The deficiency can result in red blood cell destruction and hemolysis. Symptoms often occur after consuming fava beans, a condition known as "favism". G6PD deficiency is an X-linked genetic disorder, with male carriers usually exhibiting a dominant phenotype. Female carriers with homozygous or compound heterozygous mutations can also manifest as dominant phenotype. However, most female carriers with a single heterozygous mutation are asymptomatic carriers, and only a small percentage may develop G6PD deficiency. Patients with G6PD deficiency are unable to metabolize glucose properly, as G6PD is the rate-limiting enzyme in the pentose phosphate pathway. Exposure to oxidative substances such as fava beans, aspirin and sulfonamide drugs can trigger acute
hemolytic reactions, leading to symptoms such as jaundice, mental impairment, and , in severe cases, rapid breathing heart failure, and shock, which can be life-threatening. The measurement of G6PD enzyme activity is of great clinical significance.

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